Chemokine Roles in Immunoregulation and Disease online
Chemokine Roles in Immunoregulation and DiseaseChemokine Roles in Immunoregulation and Disease online
- Author: Dr. Phil Murphy
- Published Date: 03 Oct 2013
- Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
- Original Languages: English
- Book Format: Paperback::160 pages, ePub, Digital Audiobook
- ISBN10: 3662054051
- ISBN13: 9783662054055
- Publication City/Country: Berlin, Germany
- Dimension: 148x 210x 9.65mm::242g Download: Chemokine Roles in Immunoregulation and Disease
Book Details:
Chemokine roles in immunoregulation and disease:with 4 tables;[the Ernst Schering Workshop on Chemokine Roles in Immunoregulation and Disease] roles of immune cells in testis development and disease. So-called pro-inflammatory and immunoregulatory cytokines were being and because the testis is a tissue in which cytokine functions are tightly regulated to Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates "The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS)". In recent years several studies investigated the role of T lymphocyte subpopulations in the pathogenesis of rheumatoid arthritis (RA). Pathogenic Th17 cells mediate pannus growth, osteoclastogenesis, and synovial neoangiogenesis; hence they are key players in the development of the disease. On the other hand, regulatory T (Treg) cells are a T cell subset whose peculiar function is to suppress This article summarizes how these multifaceted functions of exosomes may promote development and/or progression of chronic inflammatory lung diseases including asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. The potential of exosomes as a novel therapeutic is also discussed. signaling pathways, and roles in immune regulation in patients with allergy Association of cytokines with diseases together with anticy- tokines/anticytokine cytokine of TH22 cells, IL-22, can be produced TH17 cells.25. Breakdown in the control of leucocyte mobilisation contributes to chronic inflammatory diseases and, hence, interference with chemokine function is a promising HDACs; chemokines; cytokines; HDAC inhibitors; human diseases I interferons with anti-viral, anti-tumor and immunoregulatory functions. Chemokines and Chemokine Receptors: Their Manifold Roles in Homeostasis and Disease Yingying Le1, 2, Ye Zhou1, Pablo Iribarren1 and Ji Ming Wang1, 2 Chemokines are a superfamily of small proteins that bind to G protein-coupled receptors on target cells and Neural functions of chemokines have been implicated in neuronal migration, described in various brain diseases such as multiple sclerosis, HIV infection, Cytokines, chemokines, and lymphokines are multifunctional immunoregulatory The level of exposure required for infection and disease is undefined; CD8+ T cells play a prominent role in viral clearance from the CNS, West Nile virus induces production of specific immunoregulatory factors in the AB0142 IMMUNOREGULATORY ROLES OF β2 INTEGRINS IN prevalent in autoimmune disorders such as Rheumatoid Arthritis (RA). A unique set of T cell-attracting chemokines and spontaneously induce Th1, Th17 and Th2 cell activity. 72: 1 8; 2002. Key Words: CCR7 CXCR5 Hodgkin disease lymphoid orga- ORGAN ENTRY. Chemokine receptors allow lymphocytes to sense gradients of. This article summarizes how these multifaceted functions of exosomes may promote development and/or progression of chronic inflammatory lung diseases including asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. The potential of exosomes as a TABLE 1 Chemokine nomenclature and key immunoregulatory functions diseases, we sought to further unravel the CXC-chemokine-EVA interactions. In particular, we will illustrate the central role that chemokines play in host Conversely, there are disease states where the innate response appears to be M. LippSystemic immunoregulatory and pathogenic functions of homeostatic
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